Chronic inflammatory systemic diseases are the result of the body's immune imbalance. Immunosuppressants are the main treatment, but unfortunately, not all patients respond well to it. Being capable of self-renewal and differentiation into multiple tissue cells and low immunogenicity, mesenchymal stem cell is a promising treatment for chronic inflammatory systemic diseases.

Chronic inflammatory systemic disease (CID) is a collective term for diseases characterized by prolonged inflammation lasting from several months to years. They include asthma, cancer, heart disease, rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythematosus among others. Most treatments for these conditions have serious and/or undesirable side effects, while stem cell therapy reduces inflammation significantly with no known side effects from Alzheimer's disease.

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